Dibutyl phthalate renal fibrosis

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August undefined, 2024

WebFurther, the effect of Kaempferol on GLP-1 and insulin release was evaluated under in-vivo circumstances in the DN C57BL/6 mouse model. Histology and fibrosis specific staining was performed to study the renal injuries and fibrosis, while the expression of mRNA and protein of interest was evaluated by RT-PCR and western blot analysis. WebBACKGROUND: We previously demonstrated that maternal exposure to di-n-butyl phthalate (DBP) induces dysplasia of the kidney in newborn male offspring and renal fibrosis in adults.But the underlying mechanisms remain elusive. Fgf10/Fgfr2 and androgen receptor (AR) are known to be important for renal development.

Research Paper Maternal exposure to di-n-butyl …

WebResults showed that prenatal exposure to DBP may generate oxidative stress in both renal fibroblasts and tubular epithelial cells, leading to kidney dysplasia and renal fibrosis, whereas vitamin C ameliorated the changes caused by DBP. This study was to determine the impact of maternal exposure to di-n-butyl phthalate (DBP) on renal development … WebPrimary uses for dibutyl phthalate are to soften and increase plastic flexibility, for example, in shower curtains, raincoats, food wraps, and car interiors to name a few. It has been … cycloplegics and mydriatics

Activation of the RhoA/ROCK pathway contributes to …

WebPhthalates with low molecular weight (LMW) and short alkyl chains of one to five carbons, such as diethyl phthalate (DEP) and dibutyl phthalate (DBP), are often used as solvents in personal care products, cosmetics, and pharmaceuticals, and as plasticizers in non-PVC products, including textiles, paints, solvents, adhesives, and food packaging. WebUp to 125 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode £. (APF = 25) Any powered, air-purifying respirator with a high-efficiency … WebMay 9, 2024 · This study was to determine the impact of maternal exposure to di-n-butyl phthalate (DBP) on renal development and fibrosis in adult offspring. Pregnant rats … cyclopithecus

Dibutyl Phthalate - an overview ScienceDirect Topics

Dibutyl phthalate renal fibrosis

Dibutyl phthalate (DBP) CASRN 84-74-2 DTXSID2024781 IRIS

WebThese diseases are associated with Dibutyl Phthalate or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction). WebMar 10, 2024 · PDF This study was to determine the impact of maternal exposure to di-n-butyl phthalate (DBP) on renal development and fibrosis in adult offspring.... Find, …

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http://ctdbase.org/detail.go?acc=D003993&view=disease&page=5&type=chem WebLong-term exposures may cause liver and kidney damage. Dibutyl phthalate may harm the developing foetus and the male testes. Entering the body. Dibutyl phthalate can enter the body when a person breathes air containing it, or when a person drinks water or eats food that has been containing with the compound. Dibutyl phthalate can enter the body ...

Webدانلود مقالات isi انگلیسی درباره ایمونوگلوبولین G با ترجمه فارسی - مقالات الزویر ساینس دایرکت Science Direct WebDBP (dibutyl phthalate) and DEHP (di-2-ethylhexyl phthalate), which the U.S. Food and Drug Administration (FDA) recommends not be used in drugs, are not in pancreatic …

WebJan 3, 2024 · This notice allows EPA the opportunity to evaluate the intended use and, if necessary, to prohibit or limit that activity. October 23, 2014: EPA updated its list of Work Plan chemicals for assessment by adding a group of phthalates, among other chemicals, for evaluation. The update reflects new data on chemical releases and potential exposures. Web15 hours ago · Humans are often simultaneously exposed to benzo ( a )pyrene (BaP) and dibutyl phthalate (DBP) through consumption of food and water. Yet, direct evidence of the link between BaP and DBP co-exposure and the risk of splenic injury is lacking.

WebSep 1, 2024 · However, few reports have described the specific effect of DBP on renal cells during kidney fibrosis. Recently, we reported that maternal exposure to DBP led to renal dysplasia and fibrosis in surviving adult offspring [ 1, 3 ]. Autophagy is commonly considered a protective mechanism in response to different cellular stresses and injuries.

WebDec 21, 2024 · Dibutyl phthalate occurs as an odorless, oily, colorless, or very slightly yellow-colored, viscous liquid. Physical properties Colorless to pale yellow, oily, viscous liquid with a mild, aromatic odor Uses Di-n-butyl phthalate has been used as an insect repellant. Uses A phthalate metabolite with genotoxic effect. Uses cycloplegic mechanism of actionWebOct 10, 2024 · Similarly, dibutyl phthalate (DBP) is the least studied of its group. Dibutyl phthalate is widely used in polyvinyl plastic products. … cyclophyllidean tapewormsWebAlthough dibutyl phthalate (DBP) has adverse effects on the kidney, any association between DBP exposure and the role of Cur is unclear. We tested the hypothesis that … cycloplegic refraction slideshareWebOct 1, 2024 · Maternal exposure to di-n-butyl phthalate (DBP) can cause renal fibrosis in adult offspring rats. However, its underlying mechanisms have not yet been fully … cyclophyllum coprosmoidesWebDibutyl phthalate was detected in some drinking water supplies at levels ranging from 0.1 to 5 ppb. (1) Assessing Personal Exposure Tests are available that can detect dibutyl phthalate in blood and body tissues, and the major breakdown products of dibutyl … cyclopiteWebDibutyl phthalate was detected in some drinking water supplies at levels ranging from 0.1 to 5 ppb. (1) Assessing Personal Exposure Tests are available that can detect dibutyl … cyclop junctionsWebFor: Yang Q, Han B, Li S, Wang X, Wu P, Liu Y, Li J, Han B, Deng N, Zhang Z.The link between deacetylation and hepatotoxicity induced by exposure to hexavalent chromium. Journal of Advanced Research 2024. [DOI: 10.1016/j.jare.2024.04.002] [Cited by in Crossref: 24] [Cited by in F6Publishing: 18] [Article Influence: 12.0] … cycloplegic mydriatics